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Peptide library

Every peptide, mapped to the body.

191 peptides, from approved drugs to compounds still in trials, sorted by where they act. Each profile shows what it is promoted for, how strong the evidence really is, and what regulators have said.

Brain & sleep18 peptidesImmune & defense25 peptidesDigestive & weight38 peptidesBones & muscles19 peptidesHormones & metabolism32 peptidesHeart & blood22 peptidesSkin & aging22 peptidesSexual & reproductive15 peptides

Tap a body system to filter the library.

191 of 191 peptides

5-Amino-1MQ

Wellness and performance
Digestive & weight · NNMT inhibitor

A small molecule, not a peptide, sold alongside peptides for fat loss.

EvidenceAnimals

Abaloparatide

FDA-approved
Bones & muscles · Tymlos

A synthetic analog of parathyroid hormone-related protein for osteoporosis.

EvidenceFDA approved

ACE-031

In clinical trials
Bones & muscles

A decoy receptor tested for muscle diseases, stopped after bleeding side effects.

EvidenceAnimals

Acetyl hexapeptide-8

Cosmetic and topical
Skin & aging · Argireline

A six amino acid cosmetic peptide marketed as a gentle alternative to botulinum toxin.

EvidenceSmall human studies

Acetyl octapeptide-3

Cosmetic and topical
Skin & aging · SNAP-8

An eight amino acid extension of argireline, marketed for stronger anti-wrinkle effects.

EvidenceLab

Acetyl tetrapeptide-5

Cosmetic and topical
Skin & aging · Eyeseryl

A four amino acid peptide used in eye creams for puffiness and dark circles.

EvidenceLab

Afamelanotide

FDA-approved
Skin & aging · Scenesse, Melanotan I

An alpha-MSH analog implant that lets people with a rare light-sensitivity disease tolerate sun.

EvidenceFDA approved

AHK-Cu

Cosmetic and topical
Skin & aging · Copper tripeptide-3

A copper-binding tripeptide marketed for hair growth and skin thickness.

EvidenceLab

Albiglutide

FDA-approved
Digestive & weight · Tanzeum

A weekly GLP-1 receptor agonist that proved heart benefit but was withdrawn for business reasons.

EvidenceFDA approved

Amycretin

In clinical trials
Digestive & weight

An investigational single molecule from Novo Nordisk that activates both GLP-1 and amylin receptors.

EvidenceSmall human studies

Angiotensin 1-7

In clinical trials
Heart & blood · Ang-(1-7)

A seven amino acid fragment that opposes angiotensin II, studied in several conditions.

EvidenceSmall human studies

Angiotensin II

FDA-approved
Heart & blood · Giapreza

A synthetic form of the body's own blood pressure hormone, used in septic shock.

EvidenceFDA approved

AOD-9604

Wellness and performance
Digestive & weight · Tyr-hGH 177-191

A modified fragment of human growth hormone promoted for fat loss that did not work in large trials.

EvidenceSmall human studies

Apelin-13

In clinical trials
Heart & blood

A 13 amino acid peptide that strengthens the heart and widens blood vessels, studied in heart failure.

EvidenceSmall human studies

Apraglutide

In clinical trials
Digestive & weight · FE 203799

An investigational weekly GLP-2 analog for short bowel syndrome with intestinal failure.

EvidenceLarge trials

Atosiban

FDA-approved
Sexual & reproductive · Tractocile

An oxytocin receptor blocker used to delay preterm labor in Europe.

EvidenceFDA approved

Aviptadil

FDA-approved
Sexual & reproductive · Vasoactive intestinal peptide, Invicorp

A synthetic version of vasoactive intestinal peptide, used by injection with phentolamine for erectile dysfunction in some countries.

EvidenceFDA approved

Bacitracin

FDA-approved
Immune & defense

A cyclic peptide antibiotic found in many over-the-counter wound ointments.

EvidenceFDA approved

Balixafortide

In clinical trials
Heart & blood · POL6326

A cyclic peptide CXCR4 blocker tested with chemotherapy in breast cancer.

EvidenceLarge trials

Bivalirudin

FDA-approved
Heart & blood · Angiomax

A 20 amino acid blood thinner based on leech hirudin, used during heart procedures.

EvidenceFDA approved

BPC-157

Wellness and performance
Digestive & weight · Body protection compound

A 15 amino acid gut-protein fragment studied almost entirely in animals, with growing interest in compounding.

EvidenceSmall human studies

Bremelanotide

FDA-approved
Sexual & reproductive · PT-141, Vyleesi

A melanocortin receptor agonist injected before sex, approved for low desire in premenopausal women.

EvidenceFDA approved

Brilacidin

In clinical trials
Immune & defense · PMX-30063

An experimental antibiotic mimic of host defence peptides.

EvidenceSmall human studies

Buserelin

FDA-approved
Sexual & reproductive · Suprefact

A GnRH agonist used in fertility treatment and cancers in many countries.

EvidenceFDA approved

Cagrilintide

In clinical trials
Digestive & weight · CagriSema (with semaglutide)

An investigational long-acting amylin analog from Novo Nordisk, tested alone and combined with semaglutide.

EvidenceLarge trials

Calcitonin

FDA-approved
Bones & muscles · Miacalcin

A 32 amino acid hormone, usually from salmon, used for bone conditions and high calcium.

EvidenceFDA approved

Carbetocin

FDA-approved
Sexual & reproductive · Duratocin

A long-acting oxytocin analog used to prevent bleeding after childbirth outside the United States.

EvidenceFDA approved

Carnosine

Wellness and performance
Bones & muscles · Beta-alanyl-L-histidine

A natural dipeptide found at high levels in muscle and brain, sold as an antioxidant.

EvidenceSmall human studies

Carperitide

FDA-approved
Heart & blood · Hanp

A recombinant atrial natriuretic peptide used for acute heart failure in Japan.

EvidenceFDA approved

Cenderitide

In clinical trials
Heart & blood · CD-NP

A chimeric natriuretic peptide designed to protect kidney function in heart failure.

EvidenceSmall human studies

Cerebrolysin

Wellness and performance
Brain & sleep · FPF-1070

A mixture of peptides made from pig brain, used in parts of Europe and Asia after stroke and head injury.

EvidenceSmall human studies

Cetrorelix

FDA-approved
Sexual & reproductive · Cetrotide

A GnRH antagonist that prevents early ovulation during IVF.

EvidenceFDA approved

Cibinetide

In clinical trials
Brain & sleep · ARA-290

An 11 amino acid peptide derived from erythropoietin that calms inflammation without raising red blood cells.

EvidenceSmall human studies

CJC-1295

Wellness and performance
Hormones & metabolism · Modified GRF 1-29

A modified growth hormone-releasing hormone, often paired with ipamorelin.

EvidenceSmall human studies

Colistin

FDA-approved
Immune & defense · Polymyxin E

A last-resort polypeptide antibiotic for highly resistant Gram-negative infections.

EvidenceFDA approved

Collagen peptides

Wellness and performance
Bones & muscles · Hydrolyzed collagen

Short collagen fragments sold as powders to support skin, joints and bone.

EvidenceSmall human studies

Cortagen

Wellness and performance
Brain & sleep · Ala-Glu-Asp-Pro

A four amino acid peptide from the Khavinson group, proposed to help recovery of nerve cells.

EvidenceAnimals

Cortexin

Wellness and performance
Brain & sleep

A polypeptide extract from calf brain cortex used in Russia after brain injury and in children with delays.

EvidenceSmall human studies

Corticotropin

FDA-approved
Hormones & metabolism · Acthar Gel

A long-acting form of ACTH, the hormone that tells the adrenal glands to make cortisol.

EvidenceFDA approved

Cosyntropin

FDA-approved
Hormones & metabolism · Cortrosyn

The first 24 amino acids of ACTH, used as a test for adrenal insufficiency.

EvidenceFDA approved

Cyclosporine

FDA-approved
Immune & defense · Sandimmune, Neoral

An 11 amino acid cyclic peptide from a soil fungus that made organ transplantation routine.

EvidenceFDA approved

Dalbavancin

FDA-approved
Immune & defense · Dalvance

A long-acting lipoglycopeptide antibiotic given as one or two infusions.

EvidenceFDA approved

Daptomycin

FDA-approved
Immune & defense · Cubicin

A cyclic lipopeptide antibiotic from soil bacteria for serious skin and bloodstream infections.

EvidenceFDA approved

Dasiglucagon

FDA-approved
Hormones & metabolism · Zegalogue

A stable glucagon analog that does not need to be mixed before use.

EvidenceFDA approved

Davunetide

In clinical trials
Brain & sleep · AL-108, NAP

An eight amino acid peptide from activity-dependent neuroprotective protein, tested in a rare dementia.

EvidenceLarge trials

Degarelix

FDA-approved
Hormones & metabolism · Firmagon

A GnRH antagonist for advanced prostate cancer that lowers testosterone without an initial surge.

EvidenceFDA approved

Delta sleep-inducing peptide

Wellness and performance
Brain & sleep · DSIP, emideltide

A nine amino acid peptide first isolated from rabbit brain in the 1970s and tested for insomnia.

EvidenceSmall human studies

Desirudin

FDA-approved
Heart & blood · Iprivask

A recombinant version of hirudin, a leech protein, used to prevent clots after hip surgery.

EvidenceFDA approved

Desmopressin

FDA-approved
Hormones & metabolism · DDAVP, Nocdurna

A synthetic vasopressin analog that reduces urine production.

EvidenceFDA approved

Difelikefalin

FDA-approved
Skin & aging · Korsuva

A kappa opioid receptor agonist peptide that relieves itch in people on dialysis.

EvidenceFDA approved

Dihexa

Wellness and performance
Brain & sleep · PNB-0408

An experimental memory-enhancing compound derived from angiotensin IV, tested only in animals.

EvidenceAnimals

Dipeptide diaminobutyroyl benzylamide diacetate

Cosmetic and topical
Skin & aging · Syn-Ake

A tiny synthetic molecule modeled on snake venom, marketed as a topical wrinkle reducer.

EvidenceLab

Dulaglutide

FDA-approved
Digestive & weight · Trulicity

A once-weekly GLP-1 receptor agonist used in type 2 diabetes with proven heart benefit.

EvidenceFDA approved

Ecallantide

FDA-approved
Heart & blood · Kalbitor

A 60 amino acid kallikrein blocker for attacks of hereditary angioedema.

EvidenceFDA approved

Echinocandins

FDA-approved
Immune & defense · Caspofungin, micafungin, anidulafungin, rezafungin

A class of cyclic lipopeptide antifungals and first-line treatment for invasive Candida infections.

EvidenceFDA approved

Ecnoglutide

In clinical trials
Digestive & weight · XW003

An investigational weekly GLP-1 receptor agonist developed in China by Sciwind Biosciences.

EvidenceLarge trials

Efpeglenatide

In clinical trials
Digestive & weight

A long-acting GLP-1 receptor agonist that showed heart and kidney benefit in a large trial.

EvidenceLarge trials

Elamipretide

FDA-approved
Heart & blood · SS-31, Forzinity

A four amino acid peptide that targets mitochondria, approved in 2025 for Barth syndrome.

EvidenceSmall human studies

Elcatonin

FDA-approved
Bones & muscles · Elcitonin

An eel-derived calcitonin analog approved in Japan for osteoporosis pain.

EvidenceFDA approved

Eloralintide

In clinical trials
Digestive & weight · LY3841136

An investigational amylin receptor agonist from Eli Lilly in development for obesity.

EvidenceSmall human studies

Enfuvirtide

FDA-approved
Immune & defense · Fuzeon

A 36 amino acid injectable HIV drug, the first fusion inhibitor.

EvidenceFDA approved

Enlicitide

In clinical trials
Heart & blood · MK-0616

An investigational oral PCSK9 inhibitor from Merck that sharply lowers LDL cholesterol.

EvidenceLarge trials

Epitalon

Wellness and performance
Brain & sleep · Epithalon, Ala-Glu-Asp-Gly

A four amino acid peptide promoted for sleep and longevity, studied mainly by one research group.

EvidenceSmall human studies

Eptifibatide

FDA-approved
Heart & blood · Integrilin

A cyclic peptide platelet blocker modeled on rattlesnake venom, used in acute coronary syndromes.

EvidenceFDA approved

Etelcalcetide

FDA-approved
Hormones & metabolism · Parsabiv

An injected calcimimetic peptide for high parathyroid hormone in people on dialysis.

EvidenceFDA approved

Exenatide

FDA-approved
Digestive & weight · Byetta, Bydureon

The first GLP-1 receptor agonist, derived from a hormone found in Gila monster saliva.

EvidenceFDA approved

Follistatin 344

Wellness and performance
Bones & muscles · FS344

A natural protein that blocks myostatin, a brake on muscle growth, studied mostly through gene therapy.

EvidenceAnimals

FOXO4-DRI

In clinical trials
Skin & aging

A designer peptide that triggers aged senescent cells to self-destruct, shown in mice.

EvidenceAnimals

Fragment 176-191

Wellness and performance
Digestive & weight · hGH fragment 176-191

A piece of growth hormone sold for fat loss, closely related to AOD-9604.

EvidenceAnimals

Gallium Ga-68 dotatate

FDA-approved
Digestive & weight · Netspot

A radioactive peptide used in PET scans to find neuroendocrine tumors.

EvidenceFDA approved

Ganirelix

FDA-approved
Sexual & reproductive · Fyremadel

A GnRH antagonist used in IVF to prevent early ovulation.

EvidenceFDA approved

GHK-Cu

Cosmetic and topical
Skin & aging · Copper tripeptide-1

A natural copper-binding tripeptide used widely in skin creams and promoted as an injectable.

EvidenceSmall human studies

GHRP-2

Wellness and performance
Hormones & metabolism · Pralmorelin

A growth hormone-releasing peptide approved in Japan only as a diagnostic test.

EvidenceSmall human studies

GHRP-6

Wellness and performance
Hormones & metabolism

The first synthetic growth hormone secretagogue, known for making users very hungry.

EvidenceSmall human studies

Glatiramer acetate

FDA-approved
Immune & defense · Copaxone

A random mixture of four amino acids used in relapsing multiple sclerosis.

EvidenceFDA approved

Glepaglutide

In clinical trials
Digestive & weight · ZP1848

An investigational long-acting GLP-2 analog for short bowel syndrome, dosed once or twice weekly.

EvidenceLarge trials

Glucagon

FDA-approved
Hormones & metabolism · GlucaGen, Gvoke, Baqsimi

A 29 amino acid hormone used as emergency treatment for severe low blood sugar.

EvidenceFDA approved

Glutathione

Wellness and performance
Skin & aging · GSH

The body's main antioxidant, a three amino acid peptide, sold as drips, creams and skin-lightening shots.

EvidenceSmall human studies

Gonadorelin

FDA-approved
Sexual & reproductive · GnRH, Factrel

The natural ten amino acid hormone that switches on the pituitary-gonad axis.

EvidenceFDA approved

Goserelin

FDA-approved
Sexual & reproductive · Zoladex

A GnRH agonist implant for hormone-sensitive cancers and endometriosis.

EvidenceFDA approved

Hexapeptide-9

Cosmetic and topical
Skin & aging · Collaxyl

A six amino acid collagen fragment used in anti-aging creams.

EvidenceLab

Hexarelin

Wellness and performance
Hormones & metabolism

A potent growth hormone secretagogue whose effect fades quickly with repeated use.

EvidenceSmall human studies

Histrelin

FDA-approved
Sexual & reproductive · Supprelin LA, Vantas

A GnRH agonist implant that lasts a year, for early puberty and prostate cancer.

EvidenceFDA approved

Human chorionic gonadotropin

FDA-approved
Sexual & reproductive · hCG, Novarel, Pregnyl

A pregnancy hormone used in fertility treatment, and misused in weight-loss diets.

EvidenceFDA approved

Humanin

Wellness and performance
Hormones & metabolism · HN

A 24 amino acid mitochondrial peptide found in a search for protective factors in Alzheimer disease.

EvidenceAnimals

Icatibant

FDA-approved
Heart & blood · Firazyr

A ten amino acid bradykinin blocker for attacks of hereditary angioedema.

EvidenceFDA approved

Icotrokinra

In clinical trials
Immune & defense · JNJ-2113

An oral peptide that blocks the IL-23 receptor, developed for psoriasis.

EvidenceLarge trials

IGF-1 DES

Wellness and performance
Bones & muscles · IGF-1 (4-70)

A shortened form of IGF-1 used in labs, sold for local muscle growth.

EvidenceLab

IGF-1 LR3

Wellness and performance
Bones & muscles · Long R3 IGF-1

A modified IGF-1 with an 83 amino acid sequence used mainly in cell culture, sold for muscle growth.

EvidenceLab

Insulin

FDA-approved
Hormones & metabolism · Humulin, Lantus, Novolog and others

The 51 amino acid hormone that lowers blood sugar, and the first peptide drug ever used in medicine.

EvidenceFDA approved

Ipamorelin

Wellness and performance
Hormones & metabolism

A five amino acid growth hormone secretagogue popular in wellness clinics.

EvidenceSmall human studies

Irisin

Wellness and performance
Bones & muscles · FNDC5 fragment

A hormone-like protein released by muscle during exercise, with a contested role in people.

EvidenceAnimals

Kisspeptin-10

In clinical trials
Sexual & reproductive · Metastin 45-54

A ten amino acid fragment of the hormone that switches on puberty and fertility.

EvidenceSmall human studies

KPV

Wellness and performance
Digestive & weight · Lys-Pro-Val

A three amino acid fragment of alpha-MSH studied for gut and skin inflammation, mostly in animals.

EvidenceAnimals

Lanreotide

FDA-approved
Hormones & metabolism · Somatuline Depot

A long-acting somatostatin analog injected monthly for acromegaly and neuroendocrine tumors.

EvidenceFDA approved

Larazotide

In clinical trials
Digestive & weight · AT-1001

An eight amino acid peptide once tested as an add-on to a gluten-free diet in coeliac disease.

EvidenceLarge trials

Leuprolide

FDA-approved
Hormones & metabolism · Lupron, Eligard

A GnRH agonist used to shut down sex hormone production in prostate cancer, endometriosis and early puberty.

EvidenceFDA approved

Linaclotide

FDA-approved
Digestive & weight · Linzess, Constella

A 14 amino acid peptide taken by mouth that acts only inside the gut for irritable bowel syndrome with constipation.

EvidenceFDA approved

Liraglutide

FDA-approved
Digestive & weight · Victoza, Saxenda

A daily GLP-1 receptor agonist, the first of the class approved for chronic weight management.

EvidenceFDA approved

Lixisenatide

FDA-approved
Digestive & weight · Adlyxin, Lyxumia

A short-acting GLP-1 receptor agonist taken once daily, no longer sold in the United States.

EvidenceFDA approved

LL-37

Wellness and performance
Immune & defense · Cathelicidin antimicrobial peptide

The only cathelicidin in humans, an antimicrobial and wound-healing peptide produced by skin and immune cells.

EvidenceSmall human studies

Lonapegsomatropin

FDA-approved
Hormones & metabolism · Skytrofa

A weekly growth hormone prodrug for children with growth hormone deficiency.

EvidenceFDA approved

LTX-315

In clinical trials
Immune & defense · Ruxotemitide

An oncolytic peptide injected into tumors to trigger an immune attack.

EvidenceSmall human studies

Lutetium Lu-177 dotatate

FDA-approved
Digestive & weight · Lutathera

A radioactive peptide that delivers radiation directly to neuroendocrine tumors.

EvidenceFDA approved

Lutetium Lu-177 vipivotide tetraxetan

FDA-approved
Sexual & reproductive · Pluvicto

A radioactive targeted therapy for advanced prostate cancer.

EvidenceFDA approved

Maridebart cafraglutide

In clinical trials
Digestive & weight · MariTide, AMG 133

An investigational monthly injection that pairs a GLP-1 agonist with an antibody that blocks the GIP receptor.

EvidenceLarge trials

Mazdutide

In clinical trials
Digestive & weight · IBI362

A dual GLP-1 and glucagon receptor agonist developed by Innovent, approved in China for obesity.

EvidenceLarge trials

Mecasermin

FDA-approved
Hormones & metabolism · Increlex

Recombinant IGF-1 for children whose bodies cannot make or respond to it.

EvidenceFDA approved

Mechano growth factor

Wellness and performance
Bones & muscles · MGF, IGF-1Ec

A splice variant of IGF-1 released by muscle after stretch and damage, marketed for muscle growth.

EvidenceAnimals

Melanotan II

Wellness and performance
Skin & aging · MT-2

An injectable alpha-MSH analog used for tanning and libido, with known safety warnings.

EvidenceSmall human studies

MK-677

Wellness and performance
Hormones & metabolism · Ibutamoren

An oral growth hormone booster, not a peptide, widely sold alongside peptides.

EvidenceSmall human studies

Motixafortide

FDA-approved
Heart & blood · Aphexda

A CXCR4 blocker that pushes stem cells into the blood for collection before transplant.

EvidenceFDA approved

MOTS-c

Wellness and performance
Hormones & metabolism · Mitochondrial open reading frame of the 12S rRNA-c

A 16 amino acid peptide encoded by mitochondrial DNA, studied for metabolism and exercise capacity.

EvidenceAnimals

Murepavadin

In clinical trials
Immune & defense · POL7080

A first-in-class peptide antibiotic targeting Pseudomonas aeruginosa.

EvidenceSmall human studies

NAD+

Wellness and performance
Hormones & metabolism · Nicotinamide adenine dinucleotide

A coenzyme involved in cellular energy, not strictly a peptide, sold as drips and injections.

EvidenceSmall human studies

Nafarelin

FDA-approved
Sexual & reproductive · Synarel

A nasal-spray GnRH agonist for endometriosis and early puberty.

EvidenceFDA approved

Nangibotide

In clinical trials
Immune & defense · LR12

A TREM-1 inhibitor peptide tested in septic shock.

EvidenceSmall human studies

Nerinetide

In clinical trials
Brain & sleep · NA-1

A 20 amino acid peptide tested to protect brain cells during stroke.

EvidenceLarge trials

Nesiritide

FDA-approved
Heart & blood · Natrecor

A recombinant B-type natriuretic peptide once widely used in acute heart failure.

EvidenceFDA approved

NNZ-2591

In clinical trials
Brain & sleep

An investigational synthetic analog of a natural brain peptide, in development for rare neurodevelopmental disorders.

EvidenceSmall human studies

Nonapeptide-1

Cosmetic and topical
Skin & aging · Melanostatin-5

A nine amino acid peptide used in skin-lightening products.

EvidenceLab

Noopept

Wellness and performance
Brain & sleep · GVS-111

A dipeptide-like compound developed in Russia and sold as a memory aid.

EvidenceSmall human studies

Octreotide

FDA-approved
Hormones & metabolism · Sandostatin, Mycapssa

An eight amino acid analog of somatostatin used for acromegaly and neuroendocrine tumors.

EvidenceFDA approved

Oritavancin

FDA-approved
Immune & defense · Orbactiv, Kimyrsa

A long-acting lipoglycopeptide antibiotic given as a single infusion.

EvidenceFDA approved

Osteogenic growth peptide

Wellness and performance
Bones & muscles · OGP

A 14 amino acid peptide found in blood that stimulates bone formation in animals.

EvidenceAnimals

Oxyntomodulin

Wellness and performance
Digestive & weight · OXM

A natural gut hormone that activates both GLP-1 and glucagon receptors, and inspired later dual agonists.

EvidenceSmall human studies

Oxytocin

FDA-approved
Sexual & reproductive · Pitocin

A nine amino acid hormone used to start labor and control bleeding after birth.

EvidenceFDA approved

P21

Wellness and performance
Brain & sleep · P021, CNTF-derived peptide

A small peptide based on ciliary neurotrophic factor, studied in mice for memory and neurogenesis.

EvidenceAnimals

Palmitoyl hexapeptide-12

Cosmetic and topical
Skin & aging · Pal-VGVAPG

An elastin-derived peptide marketed to improve skin firmness.

EvidenceLab

Palmitoyl pentapeptide-4

Cosmetic and topical
Skin & aging · Matrixyl, Pal-KTTKS

A five amino acid fragment of collagen with a fatty acid tail, the best-studied anti-wrinkle peptide.

EvidenceSmall human studies

Palmitoyl tetrapeptide-7

Cosmetic and topical
Skin & aging · Rigin, Pal-GQPR

A four amino acid fragment of an antibody, used to calm skin inflammation signals.

EvidenceSmall human studies

Palmitoyl tripeptide-1

Cosmetic and topical
Skin & aging · Pal-GHK

GHK with a fatty acid tail to help it cross the skin barrier.

EvidenceSmall human studies

Palmitoyl tripeptide-38

Cosmetic and topical
Skin & aging · Matrixyl Synthe'6

A newer cosmetic peptide marketed to rebuild several structural proteins in skin.

EvidenceLab

Palmitoyl tripeptide-5

Cosmetic and topical
Skin & aging · Syn-Coll, Pal-KVK

A three amino acid peptide marketed to stimulate collagen production.

EvidenceLab

Palopegteriparatide

FDA-approved
Bones & muscles · Yorvipath

A long-acting prodrug of parathyroid hormone given once daily for hypoparathyroidism.

EvidenceFDA approved

Parathyroid hormone 1-84

FDA-approved
Bones & muscles · Natpara

The full-length parathyroid hormone, once used for hypoparathyroidism and now withdrawn.

EvidenceFDA approved

Pasireotide

FDA-approved
Hormones & metabolism · Signifor

A multi-receptor somatostatin analog for Cushing disease and acromegaly.

EvidenceFDA approved

PE-22-28

Wellness and performance
Brain & sleep · Spadin analog

A short synthetic peptide studied in mice as a fast-acting antidepressant.

EvidenceAnimals

PEG-MGF

Wellness and performance
Bones & muscles · Pegylated mechano growth factor

A long-acting version of mechano growth factor, studied only in animals.

EvidenceAnimals

Pegcetacoplan

FDA-approved
Heart & blood · Empaveli, Syfovre

A pegylated cyclic peptide that blocks complement C3, approved for a rare blood disorder and for an eye disease.

EvidenceFDA approved

Pegvisomant

FDA-approved
Hormones & metabolism · Somavert

A growth hormone receptor blocker for acromegaly.

EvidenceFDA approved

Pemvidutide

In clinical trials
Digestive & weight · ALT-801

An investigational GLP-1 and glucagon dual agonist from Altimmune, aimed at fatty liver disease.

EvidenceSmall human studies

Pentapeptide-18

Cosmetic and topical
Skin & aging · Leuphasyl

A five amino acid peptide resembling an enkephalin, marketed to relax expression lines.

EvidenceLab

Petrelintide

In clinical trials
Digestive & weight · ZP8396

An investigational long-acting amylin analog from Zealand Pharma and Roche.

EvidenceSmall human studies

Pexiganan

In clinical trials
Immune & defense · MSI-78, Locilex

A magainin-like peptide cream tested for infected diabetic foot ulcers.

EvidenceLarge trials

Pinealon

Wellness and performance
Brain & sleep · Glu-Asp-Arg

A three amino acid peptide from the Khavinson group, studied for brain protection.

EvidenceAnimals

Plecanatide

FDA-approved
Digestive & weight · Trulance

A 16 amino acid guanylate cyclase-C agonist for constipation and irritable bowel syndrome.

EvidenceFDA approved

PN-943

In clinical trials
Digestive & weight

An investigational oral peptide that stays in the gut and blocks immune cells from entering the bowel wall.

EvidenceSmall human studies

Polymyxin B

FDA-approved
Immune & defense

A last-resort cyclic peptide antibiotic, close relative of colistin.

EvidenceFDA approved

Pramlintide

FDA-approved
Digestive & weight · Symlin

A synthetic amylin analog injected at mealtimes alongside insulin.

EvidenceFDA approved

Protirelin

FDA-approved
Hormones & metabolism · TRH, Thyrel

Thyrotropin-releasing hormone, a three amino acid hormone from the hypothalamus.

EvidenceFDA approved

PYY 3-36

Wellness and performance
Digestive & weight · Peptide YY

A gut hormone released after eating that reduces hunger, studied for obesity but never approved.

EvidenceSmall human studies

Retatrutide

In clinical trials
Digestive & weight · LY3437943

An investigational once-weekly triple agonist of the GIP, GLP-1 and glucagon receptors from Eli Lilly.

EvidenceLarge trials

Romiplostim

FDA-approved
Heart & blood · Nplate

A peptide-antibody fusion that stimulates platelet production in immune thrombocytopenia.

EvidenceFDA approved

Rusfertide

In clinical trials
Heart & blood · PTG-300

An investigational hepcidin mimetic injected under the skin for polycythemia vera.

EvidenceLarge trials

Secretin

FDA-approved
Digestive & weight · ChiRhoStim

A 27 amino acid gut hormone used as a diagnostic test for pancreas problems.

EvidenceFDA approved

Selank

Wellness and performance
Brain & sleep · Thr-Lys-Pro-Arg-Pro-Gly-Pro

A synthetic analog of tuftsin used as a nasal anti-anxiety peptide in Russia.

EvidenceSmall human studies

Selepressin

In clinical trials
Heart & blood

A selective vasopressin V1a agonist tested in septic shock.

EvidenceLarge trials

Semaglutide

FDA-approved
Digestive & weight · Ozempic, Wegovy, Rybelsus

A once-weekly GLP-1 receptor agonist approved for type 2 diabetes, weight management and cardiovascular risk reduction.

EvidenceFDA approved

Semax

Wellness and performance
Brain & sleep · Met-Glu-His-Phe-Pro-Gly-Pro

A seven amino acid peptide derived from ACTH, used as a nasal spray in Russia after stroke.

EvidenceSmall human studies

Serelaxin

In clinical trials
Heart & blood · RLX030

Recombinant human relaxin-2, a pregnancy hormone tested in acute heart failure.

EvidenceLarge trials

Sermorelin

Wellness and performance
Hormones & metabolism · Geref

A growth hormone-releasing hormone fragment once approved for children and now compounded for adults.

EvidenceSmall human studies

Setmelanotide

FDA-approved
Digestive & weight · Imcivree

A melanocortin-4 receptor agonist for rare genetic forms of severe obesity.

EvidenceFDA approved

sh-Oligopeptide-1

Cosmetic and topical
Skin & aging · Epidermal growth factor (EGF)

Lab-made human epidermal growth factor, a 53 amino acid protein used in serums for skin repair.

EvidenceSmall human studies

Sincalide

FDA-approved
Digestive & weight · Kinevac

A synthetic fragment of the gut hormone cholecystokinin used in gallbladder and pancreas tests.

EvidenceFDA approved

Somapacitan

FDA-approved
Hormones & metabolism · Sogroya

A once-weekly growth hormone for children and adults with growth hormone deficiency.

EvidenceFDA approved

Somatrogon

FDA-approved
Hormones & metabolism · Ngenla

A weekly long-acting growth hormone for children.

EvidenceFDA approved

Somatropin

FDA-approved
Hormones & metabolism · Genotropin, Norditropin, Omnitrope

Recombinant human growth hormone, a 191 amino acid protein used for growth failure and deficiency.

EvidenceFDA approved

Survodutide

In clinical trials
Digestive & weight · BI 456906

An investigational dual glucagon and GLP-1 receptor agonist being developed for obesity and fatty liver disease.

EvidenceLarge trials

TB-500

Wellness and performance
Bones & muscles · Thymosin beta-4 fragment

A lab-made fragment of a natural repair protein promoted for tissue healing and sports injury recovery.

EvidenceAnimals

Teduglutide

FDA-approved
Digestive & weight · Gattex

A GLP-2 analog that helps the gut absorb nutrients in short bowel syndrome.

EvidenceFDA approved

Telavancin

FDA-approved
Immune & defense · Vibativ

A lipoglycopeptide antibiotic for resistant skin infections and hospital pneumonia.

EvidenceFDA approved

Teriparatide

FDA-approved
Bones & muscles · Forteo

The first 34 amino acids of parathyroid hormone, a bone-building osteoporosis drug.

EvidenceFDA approved

Terlipressin

FDA-approved
Heart & blood · Terlivaz

A vasopressin prodrug used for kidney failure in advanced liver disease.

EvidenceFDA approved

Tesamorelin

FDA-approved
Hormones & metabolism · Egrifta

A growth hormone-releasing hormone analog approved to reduce belly fat in people with HIV.

EvidenceFDA approved

Thymalin

Wellness and performance
Immune & defense

A thymus extract developed in the Soviet Union and promoted as an immune bioregulator.

EvidenceSmall human studies

Thymopentin

In clinical trials
Immune & defense · TP-5, Timunox

A five amino acid fragment of thymopoietin used as an immune modulator in parts of Europe.

EvidenceSmall human studies

Thymosin alpha 1

In clinical trials
Immune & defense · Thymalfasin, Zadaxin

A 28 amino acid thymus peptide approved in dozens of countries but not in the United States.

EvidenceLarge trials

Thymosin beta-4

In clinical trials
Bones & muscles · Tb4, RGN-259

A 43 amino acid protein present in nearly all human cells, studied for eye, heart and skin repair.

EvidenceSmall human studies

Thymulin

Wellness and performance
Immune & defense · Facteur thymique serique

A nine amino acid thymus hormone that needs zinc to work.

EvidenceAnimals

Tirzepatide

FDA-approved
Digestive & weight · Mounjaro, Zepbound

A once-weekly dual GIP and GLP-1 receptor agonist approved for type 2 diabetes, obesity and sleep apnea in obesity.

EvidenceFDA approved

Tripeptide-10 citrulline

Cosmetic and topical
Skin & aging · Decorinyl

A cosmetic peptide that imitates decorin, a protein that keeps collagen fibers evenly organized.

EvidenceLab

Triptorelin

FDA-approved
Hormones & metabolism · Trelstar, Triptodur

A GnRH agonist used for prostate cancer and central precocious puberty.

EvidenceFDA approved

Trofinetide

FDA-approved
Brain & sleep · Daybue

A synthetic analog of a small brain peptide approved for Rett syndrome.

EvidenceFDA approved

Ularitide

In clinical trials
Heart & blood · Urodilatin

A kidney-derived natriuretic peptide tested in acute heart failure and found not to help.

EvidenceLarge trials

Vancomycin

FDA-approved
Immune & defense · Vancocin

A glycopeptide antibiotic that remains a mainstay for resistant staph infections.

EvidenceFDA approved

Vasopressin

FDA-approved
Hormones & metabolism · Vasostrict

A nine amino acid hormone used to raise blood pressure in vasodilatory shock.

EvidenceFDA approved

Voclosporin

FDA-approved
Immune & defense · Lupkynis

A modified cyclosporine for lupus nephritis.

EvidenceFDA approved

Vosoritide

FDA-approved
Bones & muscles · Voxzogo

A C-type natriuretic peptide analog that increases growth in children with achondroplasia.

EvidenceFDA approved

Ziconotide

FDA-approved
Brain & sleep · Prialt

A synthetic cone snail toxin injected into the spinal fluid for severe chronic pain.

EvidenceFDA approved

Zilucoplan

FDA-approved
Immune & defense · Zilbrysq

A macrocyclic peptide that blocks complement C5, approved for generalized myasthenia gravis.

EvidenceFDA approved

How to read this library

Status shows where a peptide stands with regulators: FDA-approved drugs, compounds in clinical trials, peptides sold for wellness and performance, and cosmetic ingredients. The evidence scale shows the strongest kind of study published, from lab work to FDA approval. Inclusion is not an endorsement, and many entries are not approved for any use. For the 15 peptides under FDA compounding review, see Compounded peptides.

General information, not medical advice. Do not buy or inject unregulated peptides.