Peptide library / Hormones & metabolism / Corticotropin
Corticotropin
A long-acting form of ACTH, the hormone that tells the adrenal glands to make cortisol.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Infantile spasmsFDA approved
- Multiple sclerosis relapsesFDA approved
- Several inflammatory conditionsFDA approved
How it is thought to work
Corticotropin raises cortisol and also acts on melanocortin receptors on immune cells.
What the evidence shows
Evidence is strongest for infantile spasms. For many adult uses the evidence is older and has been criticized given the drug's high price.
Safety and unknowns
Similar to steroid side effects: high blood sugar, fluid retention, mood changes and infection risk.
Regulatory status
FDA-approved. The Acthar Gel brand has been on the market since 1952.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
More in Hormones & metabolism
Cosyntropin
FDA-approvedThe first 24 amino acids of ACTH, used as a test for adrenal insufficiency.
Dasiglucagon
FDA-approvedA stable glucagon analog that does not need to be mixed before use.
CJC-1295
Wellness and performanceA modified growth hormone-releasing hormone, often paired with ipamorelin.
General information, not medical advice. Do not buy or inject unregulated peptides.