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Peptide library / Hormones & metabolism / Cosyntropin

FDA-approvedHormones & metabolism

Cosyntropin

The first 24 amino acids of ACTH, used as a test for adrenal insufficiency.

Body system
Hormones & metabolism
Status
FDA-approved
Strongest evidence
FDA approved
Also known as
Cortrosyn

Effects studied or claimed

What it is used or promoted for, and where each effect has actually been seen

  • Diagnosis of adrenal insufficiencyFDA approved

How it is thought to work

Cosyntropin stimulates the adrenal glands to make cortisol, and failure to respond points to adrenal disease.

What the evidence shows

The standard short stimulation test has been used for decades.

Safety and unknowns

Rare allergic reactions can occur.

Regulatory status

FDA-approved as Cortrosyn in 1970.

Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.

Sources

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General information, not medical advice. Do not buy or inject unregulated peptides.