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Peptide library / Hormones & metabolism / Dasiglucagon

FDA-approvedHormones & metabolism

Dasiglucagon

A stable glucagon analog that does not need to be mixed before use.

Body system
Hormones & metabolism
Status
FDA-approved
Strongest evidence
FDA approved
Also known as
Zegalogue

Effects studied or claimed

What it is used or promoted for, and where each effect has actually been seen

  • Severe hypoglycemia rescueFDA approved
  • Congenital hyperinsulinism, studiedLarge trials

How it is thought to work

Dasiglucagon has amino acid changes that make it resistant to clumping in liquid, so it is ready to inject straight from a pen.

What the evidence shows

Trials in people with type 1 diabetes showed rapid recovery of blood glucose, similar to glucagon.

Safety and unknowns

Nausea, vomiting and injection site reactions were most common.

Regulatory status

FDA-approved as Zegalogue in 2021.

Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.

More in Hormones & metabolism

General information, not medical advice. Do not buy or inject unregulated peptides.