Peptide library / Hormones & metabolism / Desmopressin
Desmopressin
A synthetic vasopressin analog that reduces urine production.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Central diabetes insipidusFDA approved
- Night-time urination and bedwettingFDA approved
- Bleeding disorders such as mild hemophilia AFDA approved
How it is thought to work
Desmopressin selectively activates vasopressin V2 receptors in the kidney, which increases water reabsorption.
What the evidence shows
Used since the 1970s with a strong safety record when sodium is monitored.
Safety and unknowns
Low blood sodium can be serious, especially in older adults, so fluid intake must be limited.
Regulatory status
FDA-approved as DDAVP in 1978.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.