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Peptide library / Hormones & metabolism / Humanin

Wellness and performanceHormones & metabolism

Humanin

A 24 amino acid mitochondrial peptide found in a search for protective factors in Alzheimer disease.

Body system
Hormones & metabolism
Status
Wellness and performance
Strongest evidence
Animals
Also known as
HN

Effects studied or claimed

What it is used or promoted for, and where each effect has actually been seen

  • NeuroprotectionAnimals
  • Insulin sensitivityAnimals
  • Longevity, studiedAnimals

How it is thought to work

Humanin appears to protect cells from stress and toxic proteins, and to improve insulin sensitivity in animals.

What the evidence shows

Discovered in 2001. Higher levels are seen in long-lived families, but intervention evidence in people is absent.

Safety and unknowns

Human safety has not been tested in controlled trials.

Regulatory status

Not approved. Analogues are being studied in laboratories.

Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.

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General information, not medical advice. Do not buy or inject unregulated peptides.