Peptide library / Hormones & metabolism / Hexarelin
Hexarelin
A potent growth hormone secretagogue whose effect fades quickly with repeated use.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Growth hormone releaseSmall human studies
- Heart muscle protection, studiedAnimals
How it is thought to work
Hexarelin activates the ghrelin receptor and also a heart-related receptor, CD36, and was studied for effects on cardiac function.
What the evidence shows
Small human studies show a strong initial growth hormone response that diminishes within weeks, a phenomenon called desensitization.
Safety and unknowns
Raised cortisol and prolactin and water retention have been reported.
Regulatory status
Not approved. Banned in sport.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.