Peptide library / Hormones & metabolism / Ipamorelin
Ipamorelin
A five amino acid growth hormone secretagogue popular in wellness clinics.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Growth hormone releaseSmall human studies
- Faster gut recovery after surgery, studiedLarge trials
- Body composition, promotedLab
How it is thought to work
Ipamorelin activates the ghrelin receptor on the pituitary to release growth hormone with little effect on other pituitary hormones.
What the evidence shows
A phase 2 trial of an injectable form for post-surgical bowel paralysis did not show benefit. Evidence that it improves body composition in healthy adults is lacking.
Safety and unknowns
Headache, flushing and raised hunger have been reported. It is banned in sport.
Regulatory status
Not approved. Sold by compounding pharmacies and as a research chemical.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.