Peptide library / Skin & aging / Palmitoyl hexapeptide-12
Palmitoyl hexapeptide-12
An elastin-derived peptide marketed to improve skin firmness.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Improve skin firmness, topicalLab
How it is thought to work
The sequence repeats in elastin and is described as attracting fibroblasts and stimulating new elastin and collagen.
What the evidence shows
Mainly manufacturer data.
Safety and unknowns
Well tolerated.
Regulatory status
Cosmetic ingredient, not a drug.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
More in Skin & aging
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Palmitoyl tetrapeptide-7
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Nonapeptide-1
Cosmetic and topicalA nine amino acid peptide used in skin-lightening products.
General information, not medical advice. Do not buy or inject unregulated peptides.