Peptide library / Skin & aging / Nonapeptide-1
Nonapeptide-1
A nine amino acid peptide used in skin-lightening products.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Reduce dark spots, topicalLab
How it is thought to work
It competes with alpha-MSH at the melanocortin 1 receptor, reducing the signal to make melanin.
What the evidence shows
Support is mostly from cell studies and manufacturer trials.
Safety and unknowns
Well tolerated.
Regulatory status
Cosmetic ingredient, not a drug.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.