Peptide library / Hormones & metabolism / Mecasermin
Mecasermin
Recombinant IGF-1 for children whose bodies cannot make or respond to it.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Severe primary IGF-1 deficiency in childrenFDA approved
How it is thought to work
Mecasermin directly provides IGF-1, the hormone growth hormone normally induces to drive bone and tissue growth.
What the evidence shows
Treatment increases height velocity in children with Laron syndrome and related disorders.
Safety and unknowns
Low blood sugar is the main risk, and swelling of lymphoid tissue and intracranial pressure have occurred.
Regulatory status
FDA-approved as Increlex in 2005.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.