Peptide library / Heart & blood / Balixafortide
Balixafortide
A cyclic peptide CXCR4 blocker tested with chemotherapy in breast cancer.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Metastatic breast cancerLarge trials
- Stem cell mobilizationSmall human studies
How it is thought to work
Balixafortide blocks CXCR4, which tumors use to spread and resist treatment.
What the evidence shows
A phase 3 trial in breast cancer did not show the hoped-for benefit.
Safety and unknowns
Infusion reactions were reported.
Regulatory status
Not approved.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.