Peptide library / Sexual & reproductive / Goserelin
Goserelin
A GnRH agonist implant for hormone-sensitive cancers and endometriosis.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Prostate cancerFDA approved
- Breast cancer in premenopausal womenFDA approved
- EndometriosisFDA approved
How it is thought to work
Goserelin gradually releases a GnRH analog that suppresses sex hormones after an initial surge.
What the evidence shows
Implanted under the skin every one or three months. It reduced recurrence in some breast cancer settings in large trials.
Safety and unknowns
Hot flushes, loss of libido and bone loss with long use.
Regulatory status
FDA-approved as Zoladex in 1989.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
More in Sexual & reproductive
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FDA-approvedThe natural ten amino acid hormone that switches on the pituitary-gonad axis.
General information, not medical advice. Do not buy or inject unregulated peptides.