Peptide library / Sexual & reproductive / Histrelin
Histrelin
A GnRH agonist implant that lasts a year, for early puberty and prostate cancer.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Central precocious pubertyFDA approved
- Advanced prostate cancerFDA approved
How it is thought to work
Histrelin is released slowly from an implant under the skin and keeps sex hormone production switched off.
What the evidence shows
A single implant suppressed hormones for 12 months in trials.
Safety and unknowns
Implant site reactions and hot flushes.
Regulatory status
FDA-approved as Vantas (2004) and Supprelin LA (2007).
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
More in Sexual & reproductive
Human chorionic gonadotropin
FDA-approvedA pregnancy hormone used in fertility treatment, and misused in weight-loss diets.
Kisspeptin-10
In clinical trialsA ten amino acid fragment of the hormone that switches on puberty and fertility.
Goserelin
FDA-approvedA GnRH agonist implant for hormone-sensitive cancers and endometriosis.
General information, not medical advice. Do not buy or inject unregulated peptides.