Peptide library / Sexual & reproductive / Human chorionic gonadotropin
Human chorionic gonadotropin
A pregnancy hormone used in fertility treatment, and misused in weight-loss diets.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Ovulation trigger in fertility treatmentFDA approved
- Hypogonadotropic hypogonadism in menFDA approved
- Weight loss, claimedLarge trials
How it is thought to work
hCG mimics luteinizing hormone, triggering ovulation in women and testosterone production in men.
What the evidence shows
Trials of the hCG diet found no benefit over low-calorie dieting alone. The FDA warns against hCG for weight loss.
Safety and unknowns
Ovarian hyperstimulation can occur in women, and blood clots and headaches in men and women.
Regulatory status
FDA-approved for specific uses. Weight-loss use is prohibited.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.