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Peptide library / Sexual & reproductive / Kisspeptin-10

In clinical trialsSexual & reproductive

Kisspeptin-10

A ten amino acid fragment of the hormone that switches on puberty and fertility.

Body system
Sexual & reproductive
Status
In clinical trials
Strongest evidence
Small human studies
Also known as
Metastin 45-54

Effects studied or claimed

What it is used or promoted for, and where each effect has actually been seen

  • Triggering egg maturation in IVFSmall human studies
  • Low sex drive and hypothalamic amenorrheaSmall human studies

How it is thought to work

Kisspeptin drives release of GnRH from the hypothalamus, which triggers the rest of the reproductive hormone chain.

What the evidence shows

A trial in IVF found that kisspeptin triggered oocyte maturation with low risk of overstimulation. Studies are small.

Safety and unknowns

Generally well tolerated in small studies.

Regulatory status

Not approved. Under investigation.

Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.

More in Sexual & reproductive

General information, not medical advice. Do not buy or inject unregulated peptides.