Peptide library / Sexual & reproductive / Aviptadil
Aviptadil
A synthetic version of vasoactive intestinal peptide, used by injection with phentolamine for erectile dysfunction in some countries.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Erectile dysfunctionFDA approved
- Severe COVID-19 respiratory failure, studiedLarge trials
How it is thought to work
Aviptadil relaxes smooth muscle in blood vessels, increasing blood flow into penile tissue.
What the evidence shows
A COVID-19 trial of intravenous aviptadil did not show a consistent benefit. The erectile dysfunction product is injected into the penis.
Safety and unknowns
Flushing and injection-related effects.
Regulatory status
Approved in a few countries for erectile dysfunction. Not FDA-approved.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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Atosiban
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General information, not medical advice. Do not buy or inject unregulated peptides.