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Peptide library / Heart & blood / Cenderitide

In clinical trialsHeart & blood

Cenderitide

A chimeric natriuretic peptide designed to protect kidney function in heart failure.

Body system
Heart & blood
Status
In clinical trials
Strongest evidence
Small human studies
Also known as
CD-NP

Effects studied or claimed

What it is used or promoted for, and where each effect has actually been seen

  • Heart failure with kidney protectionSmall human studies

How it is thought to work

Cenderitide fuses parts of two natriuretic peptides to promote salt excretion and relax vessels without as much drop in blood pressure.

What the evidence shows

Early studies reported effects on urine output and kidney function. Larger trials were not completed.

Safety and unknowns

Low blood pressure was less common than with nesiritide in early studies.

Regulatory status

Not approved. Development stalled after early trials.

Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.

More in Heart & blood

General information, not medical advice. Do not buy or inject unregulated peptides.