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Peptide library / Hormones & metabolism / NAD+

Wellness and performanceHormones & metabolism

NAD+

A coenzyme involved in cellular energy, not strictly a peptide, sold as drips and injections.

Body system
Hormones & metabolism
Status
Wellness and performance
Strongest evidence
Small human studies
Also known as
Nicotinamide adenine dinucleotide

Full analysis available. NAD+ is under FDA compounding review, and we cover it in depth with the committee vote and our Peptide Evidence Index. Read the full NAD+ analysis →

Effects studied or claimed

What it is used or promoted for, and where each effect has actually been seen

  • Energy and anti-aging, promotedSmall human studies
  • Addiction recovery, promotedSmall human studies

How it is thought to work

NAD+ carries electrons in energy production and fuels enzymes involved in DNA repair. Levels fall with age.

What the evidence shows

Precursors such as NMN and NR raise NAD+ levels in people, but clinical benefits have been small or absent so far.

Safety and unknowns

Infusions can cause flushing, nausea and chest tightness if given quickly.

Regulatory status

Not FDA-approved as a drug. Allowed in compounding. See our full NAD+ analysis.

Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.

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General information, not medical advice. Do not buy or inject unregulated peptides.