Peptide library / Skin & aging / Palmitoyl tripeptide-38
Palmitoyl tripeptide-38
A newer cosmetic peptide marketed to rebuild several structural proteins in skin.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Reduce wrinkles and improve firmness, topicalLab
How it is thought to work
It is said to stimulate collagen I, III and IV, fibronectin and hyaluronic acid synthesis.
What the evidence shows
Mainly manufacturer data from small trials.
Safety and unknowns
Well tolerated.
Regulatory status
Cosmetic ingredient, not a drug.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
More in Skin & aging
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Cosmetic and topicalA three amino acid peptide marketed to stimulate collagen production.
Pentapeptide-18
Cosmetic and topicalA five amino acid peptide resembling an enkephalin, marketed to relax expression lines.
Palmitoyl tripeptide-1
Cosmetic and topicalGHK with a fatty acid tail to help it cross the skin barrier.
General information, not medical advice. Do not buy or inject unregulated peptides.