Peptide library / Skin & aging / Palmitoyl tripeptide-1
Palmitoyl tripeptide-1
GHK with a fatty acid tail to help it cross the skin barrier.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Improve skin firmness, topicalSmall human studies
How it is thought to work
The same collagen-signaling sequence as GHK, made more fat-soluble for deeper penetration.
What the evidence shows
Often paired with palmitoyl tetrapeptide-7, with small studies reporting wrinkle reduction.
Safety and unknowns
Well tolerated.
Regulatory status
Cosmetic ingredient, not a drug.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
More in Skin & aging
Palmitoyl tripeptide-38
Cosmetic and topicalA newer cosmetic peptide marketed to rebuild several structural proteins in skin.
Palmitoyl tripeptide-5
Cosmetic and topicalA three amino acid peptide marketed to stimulate collagen production.
Palmitoyl tetrapeptide-7
Cosmetic and topicalA four amino acid fragment of an antibody, used to calm skin inflammation signals.
General information, not medical advice. Do not buy or inject unregulated peptides.