Peptide library / Sexual & reproductive / Cetrorelix
Cetrorelix
A GnRH antagonist that prevents early ovulation during IVF.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Prevent premature ovulation in IVFFDA approved
How it is thought to work
Cetrorelix blocks GnRH receptors, so the pituitary stops releasing the LH surge that would trigger premature ovulation.
What the evidence shows
Trials show similar pregnancy rates to agonist protocols with shorter treatment and lower risk of overstimulation.
Safety and unknowns
Injection site reactions and nausea; ovarian hyperstimulation can still occur.
Regulatory status
FDA-approved as Cetrotide in 2001.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.