Peptide library / Hormones & metabolism / Protirelin
Protirelin
Thyrotropin-releasing hormone, a three amino acid hormone from the hypothalamus.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Diagnostic test of thyroid and pituitary functionFDA approved
- Spinal cord and neurological conditions, studiedSmall human studies
How it is thought to work
Protirelin triggers the pituitary to release thyroid-stimulating hormone and prolactin, and was used to test pituitary function.
What the evidence shows
The longer-acting analog taltirelin is approved in Japan for spinocerebellar degeneration.
Safety and unknowns
Nausea, flushing and a transient rise in blood pressure after injection.
Regulatory status
Was approved as a diagnostic in the United States but is no longer marketed there.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.