Peptide library / Skin & aging / Hexapeptide-9
Hexapeptide-9
A six amino acid collagen fragment used in anti-aging creams.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Reduce wrinkles, topicalLab
How it is thought to work
It copies a repeating sequence in collagen and is described as signaling skin cells to make new collagen and repair the skin's base layer.
What the evidence shows
Support comes mostly from manufacturer studies.
Safety and unknowns
Well tolerated in topical products.
Regulatory status
Cosmetic ingredient, not a drug.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
More in Skin & aging
Melanotan II
Wellness and performanceAn injectable alpha-MSH analog used for tanning and libido, with known safety warnings.
Nonapeptide-1
Cosmetic and topicalA nine amino acid peptide used in skin-lightening products.
Glutathione
Wellness and performanceThe body's main antioxidant, a three amino acid peptide, sold as drips, creams and skin-lightening shots.
General information, not medical advice. Do not buy or inject unregulated peptides.