Peptide library / Skin & aging / Glutathione
Glutathione
The body's main antioxidant, a three amino acid peptide, sold as drips, creams and skin-lightening shots.
Full analysis available. Glutathione is under FDA compounding review, and we cover it in depth with the committee vote and our Peptide Evidence Index. Read the full Glutathione analysis →
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Antioxidant supportSmall human studies
- Skin lightening, promotedSmall human studies
How it is thought to work
Glutathione neutralizes reactive oxygen molecules and helps detoxify drugs in the liver. It also affects the type of melanin made by skin cells.
What the evidence shows
Small trials of oral and injected glutathione reported modest effects on skin tone, but the quality of evidence is low.
Safety and unknowns
The FDA and international agencies have warned about intravenous use for skin lightening because of serious reactions.
Regulatory status
Sold as a supplement. Allowed in compounding. See our full Glutathione profile.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.