Peptide library / Skin & aging / Tripeptide-10 citrulline
Tripeptide-10 citrulline
A cosmetic peptide that imitates decorin, a protein that keeps collagen fibers evenly organized.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Skin suppleness, topicalLab
How it is thought to work
It is designed to regulate how collagen fibers form and line up, which may improve skin suppleness.
What the evidence shows
Support comes from manufacturer studies.
Safety and unknowns
Well tolerated.
Regulatory status
Cosmetic ingredient, not a drug.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
More in Skin & aging
Acetyl hexapeptide-8
Cosmetic and topicalA six amino acid cosmetic peptide marketed as a gentle alternative to botulinum toxin.
Acetyl octapeptide-3
Cosmetic and topicalAn eight amino acid extension of argireline, marketed for stronger anti-wrinkle effects.
sh-Oligopeptide-1
Cosmetic and topicalLab-made human epidermal growth factor, a 53 amino acid protein used in serums for skin repair.
General information, not medical advice. Do not buy or inject unregulated peptides.