Peptide library / Heart & blood / Selepressin
Selepressin
A selective vasopressin V1a agonist tested in septic shock.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Septic shockLarge trials
How it is thought to work
Selepressin narrows blood vessels without the kidney water-retaining effects of vasopressin.
What the evidence shows
The SEPSIS-ACT trial was stopped for futility, with no improvement in key outcomes.
Safety and unknowns
Similar to placebo in the trial.
Regulatory status
Not approved. Development ended.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.