Peptide library / Digestive & weight / Secretin
Secretin
A 27 amino acid gut hormone used as a diagnostic test for pancreas problems.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Diagnosis of pancreatic exocrine dysfunctionFDA approved
- Aid in identifying gastrinomaFDA approved
- Autism treatment, claimedLab
How it is thought to work
Secretin is released in the small intestine and triggers the pancreas to secrete bicarbonate-rich fluid, which can be measured to test pancreatic function.
What the evidence shows
Secretin was the first hormone ever discovered, in 1902. Several controlled trials tested it as a treatment for autism and found no benefit over placebo.
Safety and unknowns
Short-term effects such as flushing and nausea can occur during testing.
Regulatory status
FDA-approved as a diagnostic agent. It is not approved as a treatment for any condition.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.