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Peptide library / Digestive & weight / Eloralintide

In clinical trialsDigestive & weight

Eloralintide

An investigational amylin receptor agonist from Eli Lilly in development for obesity.

Body system
Digestive & weight
Status
In clinical trials
Strongest evidence
Small human studies
Also known as
LY3841136

Effects studied or claimed

What it is used or promoted for, and where each effect has actually been seen

  • Weight loss in obesitySmall human studies

How it is thought to work

Eloralintide activates amylin receptors to promote fullness and slow gastric emptying, and may be combined with incretin drugs.

What the evidence shows

A phase 2 study reported weight loss approaching 20 percent at 48 weeks in the top dose group. Phase 3 plans have been announced.

Safety and unknowns

Nausea and vomiting were the main effects. Longer-term data are lacking.

Regulatory status

Not approved. Development has moved toward phase 3.

Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.

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General information, not medical advice. Do not buy or inject unregulated peptides.