Peptide library / Bones & muscles / Calcitonin
Calcitonin
A 32 amino acid hormone, usually from salmon, used for bone conditions and high calcium.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Paget disease of boneFDA approved
- HypercalcemiaFDA approved
- Postmenopausal osteoporosisFDA approved
How it is thought to work
Calcitonin reduces the activity of osteoclasts, the cells that break down bone, and lowers blood calcium.
What the evidence shows
Its fracture-prevention benefit is modest. Regulators reviewed a small signal of increased cancer risk with long-term use of the nasal spray, leading to more limited use.
Safety and unknowns
Nausea and facial flushing from injections. Nasal spray can irritate the nose.
Regulatory status
FDA-approved as Miacalcin in 1986.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
More in Bones & muscles
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ACE-031
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General information, not medical advice. Do not buy or inject unregulated peptides.