Peptide library / Bones & muscles / Vosoritide
Vosoritide
A C-type natriuretic peptide analog that increases growth in children with achondroplasia.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Height growth in achondroplasiaFDA approved
How it is thought to work
Vosoritide counteracts the overactive FGFR3 signaling that limits growth of cartilage in the growth plates.
What the evidence shows
A phase 3 trial reported an extra 1.6 cm of growth per year compared with placebo.
Safety and unknowns
Low blood pressure, injection site reactions and vomiting.
Regulatory status
FDA-approved as Voxzogo in 2021.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.