Peptide library / Heart & blood / Angiotensin II
Angiotensin II
A synthetic form of the body's own blood pressure hormone, used in septic shock.
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Septic or distributive shockFDA approved
How it is thought to work
Angiotensin II tightens blood vessels and triggers aldosterone release, raising blood pressure when other agents are not enough.
What the evidence shows
The ATHOS-3 trial showed more patients reached target blood pressure than with placebo.
Safety and unknowns
Blood clots are a risk, so clot prevention is recommended.
Regulatory status
FDA-approved as Giapreza in 2017.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.