Peptide library / Brain & sleep / Dihexa
Dihexa
An experimental memory-enhancing compound derived from angiotensin IV, tested only in animals.
Full analysis available. Dihexa is under FDA compounding review, and we cover it in depth with the committee vote and our Peptide Evidence Index. Read the full Dihexa analysis →
Effects studied or claimed
What it is used or promoted for, and where each effect has actually been seen
- Memory in animal modelsAnimals
- Cognitive decline in Alzheimer modelsAnimals
How it is thought to work
Dihexa binds hepatocyte growth factor and boosts its activity at the c-Met receptor, which promotes new connections between nerve cells.
What the evidence shows
Rat studies showed improvement in memory tests. There are no human trials.
Safety and unknowns
Because c-Met signaling is involved in tumor growth, cancer promotion is a theoretical concern. Human safety is unknown.
Regulatory status
Not FDA-approved. See our full Dihexa profile.
Regulatory status changes quickly. This entry was last reviewed on 27 October 2026. Confirm current status with the FDA before relying on it.
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General information, not medical advice. Do not buy or inject unregulated peptides.